Butterbur plant extract is commonly used in Europe for the treatment of hay fever. A prospective, randomized, double-blind study compared butterbur to fexofenadine (Allegra) and placebo in 330 participants with allergies (allergic rhinitis). The butterbur group took one tablet (8 mg of the active ingredient petasine) three times daily. Both fexofenadine (Allegra) and butterbur were superior to placebo in relieving symptoms. Another study found butterbur extract to be effective in relieving nasal symptoms associated with allergies. It was also shown after five days of use to significantly reduce the allergenic substance histamine. In addition, a randomized, double-blind, parallel group comparison found butterbur to be as effective as cetirizine (Zyrtec) in treating seasonal allergic rhinitis (hay fever).
Butterbur Usage Dosage
For allergic rhinitis, use a standardized extract containing 8 to 16 mg of peta- sine taken three to four times daily. Also, a whole butterbur root extract at a dose of 50 mg twice daily has been studied and can be used as well.
Butterbur Safety
Butterbur is well tolerated. It can cause digestive upset, headache, fatigue, and itchy eyes.